A.G.E. Interrupter Advanced For Ageing

Anti-wrinkle cream for Dry Skin

A.G.E. Interrupter Advanced is rated 4.5 out of 5 by 247.

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A.G.E. Interrupter Advanced is a potent corrective cream that helps reverse visible signs of ageing ... Read more

RECOMMENDED FOR

• Dry

• Normal

• Combination

• Sensitive

• Ageing

A.G.E. Interrupter Advanced For Ageing

Anti-wrinkle cream for Dry Skin

48 ml

Old price New price £175.00

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A.G.E. Interrupter Advanced Benefits

Helps address the multi-phase glycation
process known to visibly age skin

Smooths an extended range of visible wrinkle types, including fine lines, deep wrinkles, and location-specific creases like nasolabial folds

Helps restore skins firmness and elasticity, which is known to decline as glycation degrades skin's collagen

Enhances skin's overall radiance, improves tone, and reduces blotchiness for a healthier-looking complexion

Delivers rich hydration, with a luxurious,
satin finish

Free of parabens, drying alcohol, and dyes

Anti-wrinkle cream for Dry Skin

Discover A.G.E Interrupter Advanced an anti-ageing cream that targets visible ageing, which helps improves the appearance of wrinkling and restores the skin's firmness

A.G.E. Interrupter Advanced is a potent corrective cream that helps reverse visible signs of ageing impacted by collagen decline and glycation, including wrinkling, laxity, and dullness. This next-generation anti-wrinkle cream is formulated with 18% concentrated Proxylane (+20% more than previous A.G.E. Interrupter ), 4.25% wild fruit flavonoid blend (12.5% more), and new 0.1% glycyrrhetinic acid. This advanced technology is clinically shown to help improve the appearance of wrinkles, help restore the skin's firmness, and enhance skin's radiance. *Due to the formulas high levels of flavonoids, this cream's colour may vary but will remain effective.

HOW TO USE >

FAQS >

SCIENCE + PROOF

Visible Results

Interrupter Advanced improved attributes associated with skin ageing and glycation, including lines and deep wrinkles in five facial zones.

Protocol: A 12-week, single-center, clinical study was conducted on 77 females with Fitzpatrick type I-VI, ages 35-75, and mild to moderate global wrinkles, fine lines, laxity, rough skin texture, uneven skin tone, and a dull complexion. A.G.E. Interrupter Advanced was used twice daily over face, neck, and chest in conjunction with a sunscreen for 12 weeks. Efficacy and tolerance evaluations were conducted at baseline, weeks 4, 8, and 12.

Close-up of a forehead and eyebrows, showcasing the skin texture and hair before a cosmetic treatment.

Visible Results

The Science Behind
A.G.E. Interrupter Advanced For Ageing

What is Skin Glycation?

Glycation is natural process that accelerates visible signs of Ageing. During the glycation process, excess sugars bind to skin-supporting proteins (like collagen and elastin) and form advanced glycation end-products (A.G.E.s). A.G.E.s weaken collagen, leading to wrinkles and laxity.

Signs of Glycation
1. Wrinkling and crepiness
2. Loss of firmness
3. Dull, sallow complexion

Glycation Dos and Don’ts

DO: Wear Sunscreen
Protect skin from UV damage (add a link https://www.skinceuticals.co.uk/en_GB/suncare) and oxidative stress by applying broad-spectrum sunscreen daily.

DO: Reduce Sugar
Alcohol consumption and high-sugar diets can promote the glycation process. HEADER 3: DON’T: Expose Skin to SmokeCOPY 3: Cigarette smoke deposits a myriad of chemicals onto the skin in addition to speeding up the glycation process.

Physician's Insight

"We know that moisturisers help replenish the lipids around the skin, keep the skin supple and hydrated."

Dr. Wassim Taktouk

Cosmetic Doctor

Dr. Wassim Taktouk

Cosmetic Doctor

Key Ingredients

Drying Alcohol-Free

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18% Concentrated Proxylane

Helps support skin’s integrity and correct visible signs of Ageing, like wrinkles and laxity.

4.25% Wild Fruit Flavonoids

Combination of blueberry and pomegranate extracts help reduce oxidative stresCB3:CD3s, which can be linked to A.G.E. formation, and protect against free radical damage.

0.1% Glycyrrhetinic Acid

Helps counter dull tone, which can be linked to A.G.E. accumulation, and is known for its soothing properties.

3% Hepes

Activates natural enzymes in skin to promote even cell turnover while hydrating skin.

Abstract close-up of a textured, light-colored surface with undulating lines and shapes, creating a fluid appearance.

1% Niacinamide

Water-soluble vitamin, also known as vitamin B3, soothes and helps support skin’s moisture barrier.

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How to Use A.G.E. Interrupter Advanced

Prep + Dispense

Twice daily, massage a thin, even layer of A.G.E. Interrupter Advanced wrinkle cream onto the entire face, neck, and chest.

Apply + Complete

If using in the morning, apply after a SkinCeuticals vitamin C antioxidant serum and before a SkinCeuticals sunscreen. If using with a retinol at night, apply after retinol application.

Answers to your frequently asked
A.G.E. Interrupter Advanced questions.

Like A.G.E. Interrupter, A.G.E. Interrupter Advanced is a wrinkle cream that fights glycation. A.G.E. Interrupter Advanced includes an increased concentration of Proxylane as well as additional efficacious ingredients in glycyrrhetinic acid HEPES that bring forth anti-glycation science and collagen decline reversal. The texture of A.G.E. Interrupter Advanced is the same as A.G.E. Interrupter, but the new formulation does have a different smell.

Glycation, a major factor of intrinsic and extrinsic Ageing, occurs when excess sugar molecules bind to collagen and elastin fibers and prompt the formation of advanced glycation end-products (A.G.E.). As a result, glycated collagen and elastin fibers lose the ability to function normally, and the body cannot break them down and replace them, leading to severe wrinkling of the skin.

Complete Your A.G.E. Interrupter Advanced Routine

Step 1: Prevent

AWARD WINNER

C E Ferulic For Visible Signs of Ageing

Vitamin C Antioxidant Serum For Normal & Dry Skin Types

One size

30 ml

Old price New price £169.00

(£563.33/100 ml.)

Step 2: Correct

Hyaluronic Acid Intensifier Multi-Glycan

New Formula

Hyaluronic Acid Intensifier Multi-Glycan

A hyaluronic acid volumising and plumping serum.

One size

30 ml

Old price New price £120.00

(£400.00/100 ml.)

Step 3: Correct

A.G.E. Interrupter Advanced For Ageing

Anti-wrinkle cream for Dry Skin

One size

48 ml

Old price New price £175.00

(£364.58/100 ml.)

Step 4: Protect

Ultra Facial Defense SPF 50+ Facial Sunscreen for Ageing and Discolouration-Prone Skin 30ml

A moisturising, daily-use sunscreen, helps prevent sun-induced discoloration and aging.

One size

30 ml

Old price New price £50.00

(£166.67/100 ml.)

Step 1: Prevent

Resveratrol B E Night Serum For Ageing Skin

Nightime Antioxidant Serum For Dry & Normal Skin Types

One size

30 ml

Old price New price £164.00

(£546.67/100 ml.)

Step 2: Correct

New Formula

Hyaluronic Acid Intensifier Multi-Glycan

A hyaluronic acid volumising and plumping serum.

One size

30 ml

Old price New price £120.00

(£400.00/100 ml.)

Step 3: Correct

A.G.E. Interrupter Advanced For Ageing

Anti-wrinkle cream for Dry Skin

One size

48 ml

Old price New price £175.00

(£364.58/100 ml.)

Step 4: Correct

A.G.E. Advanced Eye for Dark Circles & Wrinkles

Best Seller

A.G.E. Advanced Eye For Dark Circles

Eye cream suitable for Dry & Normal Skin

One size

15 ml

Old price New price £109.00

(£726.67/100 ml.)

Rated 5 out of 5 by MélanieA from Très bien [Cet avis a été recueilli en réponse à une offre.] Je suis absolument ravie de cette crème , des les premières utilisations j'ai remarqué que ma peu était beaucoup plus douce et confortable. Sa texture est riche sans être trop lourde., elle pénètre bien et laisse la peau bien hydratée toute la journée. Au fil des jours mon teint est devenu plus lumineux et les petites ridules semblent estompées

Date published: 2026-04-08

Rated 5 out of 5 by DelphineS from Une très belle découverte que je recommande à cell [Cet avis a été recueilli en réponse à une offre.] J’utilise la crème A.G.E. Interrupter Advanced de SkinCeuticals depuis quelque temps et j’en suis très satisfaite. Sa texture est particulièrement agréable : riche sans être trop lourde, elle fond bien sur la peau et apporte une sensation immédiate de confort. J’apprécie aussi beaucoup son odeur, douce et discrète, qui rend l’application encore plus plaisante au quotidien. C’est un vrai moment de soin. Au fil des utilisations, ma peau me paraît plus souple, mieux hydratée et visiblement plus lisse.

Date published: 2026-04-08

Rated 5 out of 5 by JulieB from Douce et efficace [Cet avis a été recueilli en réponse à une offre.] Crème hydratante à la texture toute douce.Ne colle pas, facile à etaler. Ingrédients de qualité, ma peau a rajeunit en quelques jours. Plus souple, moins marquée, moins dilaté. Elle ne me tiraille plus du tout.! L'emballage est pratique, un petit pot en verre avec 2 petits couvercles.

Date published: 2026-04-08

Rated 4 out of 5 by SzymaniakC from Très bonne crème pour peau déshydratée et mâture [Cet avis a été recueilli en réponse à une offre.] Crème de très bonne qualité, on le voit par sa texture qui est ni liquide, ni épaisse . Quand on l applique on sent bien l hydratation de la peau qui dure la journée. Aucune réaction de peau et pourtant jai une peau très sensible. Elle a une petite odeur légère et très agréable . Je trouve ma peau plus hydratée plus lumineuse , mes rides sont un peu moins visible car je trouve ma peau plus repulpée a voir dans la durée en tout cas j adore et j adére.

Date published: 2026-04-08

Rated 5 out of 5 by CarolineP from Belle découverte skincare [Cet avis a été recueilli en réponse à une offre.] Première impression : le packaging est très élégant et la texture de la crème est riche mais agréable sur la peau. Elle pénètre bien sans laisser de sensation grasse. Après quelques applications, ma.peau paraît plus douce, hydratée et confortable. J'aime aussi le fait que cette crème soit conçue pour aider à réduire l'apparence des rides et améliorer la fermeté de la peau. Je suis impatiente de continuer à l'utiliser pour voir les résultats sur le long terme. Pour l'instant c'est une très belle découverte dans ma routine skincare !

Date published: 2026-04-08

Rated 5 out of 5 by Anonymous from gage de rajeunissement très bonne crème ,très efficace, même si la texture est particuliere

Date published: 2026-04-08

Rated 5 out of 5 by NadegeC from Super produit [Cet avis a été recueilli en réponse à une offre.] Lisse visiblement les rides et ridules et amélioré la densité et la fermeté de la peau. Texture nourrissante avec effet de peau repulpee avec un fini satiné agréable. Dommage que le produit soit si cher.

Date published: 2026-04-07

Rated 5 out of 5 by JoachimC from Texture poudrée , hydratation parfaite [Cet avis a été recueilli en réponse à une offre.] Quelle belle découverte , une crème anti âge avec une texture remarquable, un fini non gras avec un effet poudré. L’hydratation dure dans le temps . Un packaging sobre et classe avec son effet de verre polis. Une marque qui mérite d’être connue et reconnue .

Date published: 2026-04-05

A.G.E. Interrupter Advanced Reviews - page 2

A.G.E. Interrupter Advanced For Ageing

A.G.E. Interrupter Advanced Benefits

Anti-wrinkle cream for Dry Skin

SCIENCE + PROOF

Visible Results

Visible Results

The Science Behind
A.G.E. Interrupter Advanced For Ageing

What is Skin Glycation?

Glycation Dos and Don’ts