A.G.E. Interrupter Advanced For Ageing

Anti-wrinkle cream for Dry Skin

A.G.E. Interrupter Advanced is rated 4.5 out of 5 by 270.

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A.G.E. Interrupter Advanced is a potent corrective cream that helps reverse visible signs of ageing ... Read more

RECOMMENDED FOR

• Dry

• Normal

• Combination

• Sensitive

• Ageing

A.G.E. Interrupter Advanced For Ageing

Anti-wrinkle cream for Dry Skin

48 ml

Old price New price £175.00

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A.G.E. Interrupter Advanced Benefits

Helps address the multi-phase glycation
process known to visibly age skin

Smooths an extended range of visible wrinkle types, including fine lines, deep wrinkles, and location-specific creases like nasolabial folds

Helps restore skins firmness and elasticity, which is known to decline as glycation degrades skin's collagen

Enhances skin's overall radiance, improves tone, and reduces blotchiness for a healthier-looking complexion

Delivers rich hydration, with a luxurious,
satin finish

Free of parabens, drying alcohol, and dyes

Anti-wrinkle cream for Dry Skin

Discover A.G.E Interrupter Advanced an anti-ageing cream that targets visible ageing, which helps improves the appearance of wrinkling and restores the skin's firmness

A.G.E. Interrupter Advanced is a potent corrective cream that helps reverse visible signs of ageing impacted by collagen decline and glycation, including wrinkling, laxity, and dullness. This next-generation anti-wrinkle cream is formulated with 18% concentrated Proxylane (+20% more than previous A.G.E. Interrupter ), 4.25% wild fruit flavonoid blend (12.5% more), and new 0.1% glycyrrhetinic acid. This advanced technology is clinically shown to help improve the appearance of wrinkles, help restore the skin's firmness, and enhance skin's radiance. *Due to the formulas high levels of flavonoids, this cream's colour may vary but will remain effective.

HOW TO USE >

FAQS >

SCIENCE + PROOF

Visible Results

Interrupter Advanced improved attributes associated with skin ageing and glycation, including lines and deep wrinkles in five facial zones.

Protocol: A 12-week, single-center, clinical study was conducted on 77 females with Fitzpatrick type I-VI, ages 35-75, and mild to moderate global wrinkles, fine lines, laxity, rough skin texture, uneven skin tone, and a dull complexion. A.G.E. Interrupter Advanced was used twice daily over face, neck, and chest in conjunction with a sunscreen for 12 weeks. Efficacy and tolerance evaluations were conducted at baseline, weeks 4, 8, and 12.

Close-up of a forehead and eyebrows, showcasing the skin texture and hair before a cosmetic treatment.

Visible Results

The Science Behind
A.G.E. Interrupter Advanced For Ageing

What is Skin Glycation?

Glycation is natural process that accelerates visible signs of Ageing. During the glycation process, excess sugars bind to skin-supporting proteins (like collagen and elastin) and form advanced glycation end-products (A.G.E.s). A.G.E.s weaken collagen, leading to wrinkles and laxity.

Signs of Glycation
1. Wrinkling and crepiness
2. Loss of firmness
3. Dull, sallow complexion

Glycation Dos and Don’ts

DO: Wear Sunscreen
Protect skin from UV damage (add a link https://www.skinceuticals.co.uk/en_GB/suncare) and oxidative stress by applying broad-spectrum sunscreen daily.

DO: Reduce Sugar
Alcohol consumption and high-sugar diets can promote the glycation process. HEADER 3: DON’T: Expose Skin to SmokeCOPY 3: Cigarette smoke deposits a myriad of chemicals onto the skin in addition to speeding up the glycation process.

Physician's Insight

"We know that moisturisers help replenish the lipids around the skin, keep the skin supple and hydrated."

Dr. Wassim Taktouk

Cosmetic Doctor

Dr. Wassim Taktouk

Cosmetic Doctor

Key Ingredients

Drying Alcohol-Free

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18% Concentrated Proxylane

Helps support skin’s integrity and correct visible signs of Ageing, like wrinkles and laxity.

4.25% Wild Fruit Flavonoids

Combination of blueberry and pomegranate extracts help reduce oxidative stresCB3:CD3s, which can be linked to A.G.E. formation, and protect against free radical damage.

0.1% Glycyrrhetinic Acid

Helps counter dull tone, which can be linked to A.G.E. accumulation, and is known for its soothing properties.

3% Hepes

Activates natural enzymes in skin to promote even cell turnover while hydrating skin.

Abstract close-up of a textured, light-colored surface with undulating lines and shapes, creating a fluid appearance.

1% Niacinamide

Water-soluble vitamin, also known as vitamin B3, soothes and helps support skin’s moisture barrier.

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How to Use A.G.E. Interrupter Advanced

Prep + Dispense

Twice daily, massage a thin, even layer of A.G.E. Interrupter Advanced wrinkle cream onto the entire face, neck, and chest.

Apply + Complete

If using in the morning, apply after a SkinCeuticals vitamin C antioxidant serum and before a SkinCeuticals sunscreen. If using with a retinol at night, apply after retinol application.

Answers to your frequently asked
A.G.E. Interrupter Advanced questions.

Like A.G.E. Interrupter, A.G.E. Interrupter Advanced is a wrinkle cream that fights glycation. A.G.E. Interrupter Advanced includes an increased concentration of Proxylane as well as additional efficacious ingredients in glycyrrhetinic acid HEPES that bring forth anti-glycation science and collagen decline reversal. The texture of A.G.E. Interrupter Advanced is the same as A.G.E. Interrupter, but the new formulation does have a different smell.

Glycation, a major factor of intrinsic and extrinsic Ageing, occurs when excess sugar molecules bind to collagen and elastin fibers and prompt the formation of advanced glycation end-products (A.G.E.). As a result, glycated collagen and elastin fibers lose the ability to function normally, and the body cannot break them down and replace them, leading to severe wrinkling of the skin.

Complete Your A.G.E. Interrupter Advanced Routine

Step 1: Prevent

AWARD WINNER

C E Ferulic For Visible Signs of Ageing

Vitamin C Antioxidant Serum For Normal & Dry Skin Types

One size

30 ml

Old price New price £169.00

(£563.33/100 ml.)

Step 2: Correct

Hyaluronic Acid Intensifier Multi-Glycan

New Formula

Hyaluronic Acid Intensifier Multi-Glycan

A hyaluronic acid volumising and plumping serum.

One size

30 ml

Old price New price £120.00

(£400.00/100 ml.)

Step 3: Correct

A.G.E. Interrupter Advanced For Ageing

Anti-wrinkle cream for Dry Skin

One size

48 ml

Old price New price £175.00

(£364.58/100 ml.)

Step 4: Protect

Ultra Facial Defense SPF 50+ Facial Sunscreen for Ageing and Discolouration-Prone Skin 30ml

A moisturising, daily-use sunscreen, helps prevent sun-induced discoloration and aging.

One size

30 ml

Old price New price £50.00

(£166.67/100 ml.)

Step 1: Prevent

Resveratrol B E Night Serum For Ageing Skin

Nightime Antioxidant Serum For Dry & Normal Skin Types

One size

30 ml

Old price New price £164.00

(£546.67/100 ml.)

Step 2: Correct

New Formula

Hyaluronic Acid Intensifier Multi-Glycan

A hyaluronic acid volumising and plumping serum.

One size

30 ml

Old price New price £120.00

(£400.00/100 ml.)

Step 3: Correct

A.G.E. Interrupter Advanced For Ageing

Anti-wrinkle cream for Dry Skin

One size

48 ml

Old price New price £175.00

(£364.58/100 ml.)

Step 4: Correct

A.G.E. Advanced Eye for Dark Circles & Wrinkles

Best Seller

A.G.E. Advanced Eye For Dark Circles

Eye cream suitable for Dry & Normal Skin

One size

15 ml

Old price New price £109.00

(£726.67/100 ml.)

Rated 5 out of 5 by SabineJ from Très bon produit. [Cet avis a été recueilli en réponse à une offre.] La crème est très agréable à l'application. Elle pénetre rapidement et est soyeuse. Après un mois d'essai, j'ai vu un changement mais qui doit être plus important dans la durée et encore plus appréciable. L'emballage est soft et attirant. Le coût est important mais correspond à l'innovation du produit et à son efficacité dans le temps

Date published: 2026-04-30

Rated 4 out of 5 by NatachaW from Efficacité [Cet avis a été recueilli en réponse à une offre.] J’utilise cette crème depuis environ 1 mois et je vois clairement une amélioration de la fermeté de ma peau. Les rides autour de la bouche sont moins marquées et ma peau paraît plus lisse. La texture est riche mais pénètre bien, sans effet gras. C’est cher, mais une petite quantité suffit donc le pot dure longtemps. Pour moi, ça vaut l’investissement.

Date published: 2026-04-29

Rated 4 out of 5 by lauraA from Crème efficace sur les 1ers signes de l'âge. [Cet avis a été recueilli en réponse à une offre.] Une bonne crème pour freiner les premiers signes de l'âge. Même si je n'ai pas aimé la texture au toucher, elle est agréable à l'application sur la peau. Cette crème ne laisse pas un fini gras et elle sent bon. J'ai une peau sensible et réactive et je n'ai pas eu de réaction cutanée, j'ai cependant fait le choix de ne l'utiliser que le soir pour ne pas avoir à rajouter une protection solaire par dessus afin de ne pas étouffer ma peau. Elle a très bien fonctionné au niveau de mon décolleté, là où ma peau montrait les premiers signes et assez rapidement. Pour des rides et ridules plus prononcées, l'effet est visible mais moins rapidement. Même si cette crème est relativement efficace, il n'en reste pas moins que la rapport qualité/prix ne permet pas à toutes les bourses de l'utiliser.

Date published: 2026-04-28

Rated 5 out of 5 by MaïwennF from Efficacité remarquable [Cet avis a été recueilli en réponse à une offre.] Un produit haute qualité : pot ergonomique, contenu voluptueux et agréable à toucher, pénétration rapide et efficacité remarquable. Une marque au service de notre peau pour conclure.

Date published: 2026-04-26

Rated 5 out of 5 by SandrineB from Parfait [Cet avis a été recueilli en réponse à une offre.] Une crème douceur pour une hydratation maximale. La peau est douce et parfaitement hydratée. Le pot est pratique, le parfum est délicat. La crème pénétre rapidement et ne laisse pas de film gras sur la peau. Un vrai bonheur à appliquer.

Date published: 2026-04-25

Rated 5 out of 5 by JeanChristopheJ from Pénètre facilement ,odeur ,quel s enlève facilemen [Cet avis a été recueilli en réponse à une offre.] Une très bonne crème qui ne convient parfaitement tout en ayant une peau sensible , odeur ni trop forte ni trop faible ,qui pénètre facilement,il manque une spatule car ça serait plus pratique que de plonger les doigts dans le flacon car pas très hygiénique Pas vu de résultat pour le moment pas assez de recule Ne colle pas s'enlève facilement

Date published: 2026-04-25

Rated 5 out of 5 by FlorenceV from Idéal à l'approche de la cinquantaine [Cet avis a été recueilli en réponse à une offre.] Ce petit pot renferme une crème fondante, soyeuse et facile à appliquer. La texture ne colle pas et on peut très vite se maquiller en suivant. Si vous n'appreciez pas les parfums dans les crèmes, celle-ci est faite pour vous car elle n'en a quasiment pas. Niveau résultat : vraiment top, le grain de peau s'affine et la peau semble plus tonique.

Date published: 2026-04-24

Rated 5 out of 5 by Breizh56 from Super efficace Je l’utilise depuis plus de 10 ans ( avant c’était ÂGÉ INTERRUPTER

Date published: 2026-04-24

A.G.E. Interrupter Advanced Reviews - page 2

A.G.E. Interrupter Advanced For Ageing

A.G.E. Interrupter Advanced Benefits

Anti-wrinkle cream for Dry Skin

SCIENCE + PROOF

Visible Results

Visible Results

The Science Behind
A.G.E. Interrupter Advanced For Ageing

What is Skin Glycation?

Glycation Dos and Don’ts