A.G.E. Interrupter Advanced For Ageing

Anti-wrinkle cream for Dry Skin

A.G.E. Interrupter Advanced is rated 4.5 out of 5 by 160.

A.G.E. Interrupter Advanced is a potent corrective cream that helps reverse visible signs of ageing ... Read more

RECOMMENDED FOR

• Dry

• Normal

• Combination

• Sensitive

• Ageing

A.G.E. Interrupter Advanced For Ageing

Anti-wrinkle cream for Dry Skin

48 ml

Old price New price £175.00

Free Gift When You Spend £165*

Quantity

Why shop with us ?

10% off your first order
Free next day delivery on all orders over £200
2 free luxury samples with every order worth up to £44*

A.G.E. Interrupter Advanced Benefits

Helps address the multi-phase glycation
process known to visibly age skin

Smooths an extended range of visible wrinkle types, including fine lines, deep wrinkles, and location-specific creases like nasolabial folds

Helps restore skins firmness and elasticity, which is known to decline as glycation degrades skin's collagen

Enhances skin's overall radiance, improves tone, and reduces blotchiness for a healthier-looking complexion

Delivers rich hydration, with a luxurious,
satin finish

Free of parabens, drying alcohol, and dyes

Anti-wrinkle cream for Dry Skin

Discover A.G.E Interrupter Advanced an anti-ageing cream that targets visible ageing, which helps improves the appearance of wrinkling and restores the skin's firmness

A.G.E. Interrupter Advanced is a potent corrective cream that helps reverse visible signs of ageing impacted by collagen decline and glycation, including wrinkling, laxity, and dullness. This next-generation anti-wrinkle cream is formulated with 18% concentrated Proxylane (+20% more than previous A.G.E. Interrupter ), 4.25% wild fruit flavonoid blend (12.5% more), and new 0.1% glycyrrhetinic acid. This advanced technology is clinically shown to help improve the appearance of wrinkles, help restore the skin's firmness, and enhance skin's radiance. *Due to the formulas high levels of flavonoids, this cream's colour may vary but will remain effective.

HOW TO USE >

FAQS >

SCIENCE + PROOF

Visible Results

Interrupter Advanced improved attributes associated with skin ageing and glycation, including lines and deep wrinkles in five facial zones.

Protocol: A 12-week, single-center, clinical study was conducted on 77 females with Fitzpatrick type I-VI, ages 35-75, and mild to moderate global wrinkles, fine lines, laxity, rough skin texture, uneven skin tone, and a dull complexion. A.G.E. Interrupter Advanced was used twice daily over face, neck, and chest in conjunction with a sunscreen for 12 weeks. Efficacy and tolerance evaluations were conducted at baseline, weeks 4, 8, and 12.

Visible Results

The Science Behind
A.G.E. Interrupter Advanced For Ageing

What is Skin Glycation?

Glycation is natural process that accelerates visible signs of Ageing. During the glycation process, excess sugars bind to skin-supporting proteins (like collagen and elastin) and form advanced glycation end-products (A.G.E.s). A.G.E.s weaken collagen, leading to wrinkles and laxity.

Signs of Glycation
1. Wrinkling and crepiness
2. Loss of firmness
3. Dull, sallow complexion

Glycation Dos and Don’ts

DO: Wear Sunscreen
Protect skin from UV damage (add a link https://www.skinceuticals.co.uk/en_GB/suncare) and oxidative stress by applying broad-spectrum sunscreen daily.

DO: Reduce Sugar
Alcohol consumption and high-sugar diets can promote the glycation process. HEADER 3: DON’T: Expose Skin to SmokeCOPY 3: Cigarette smoke deposits a myriad of chemicals onto the skin in addition to speeding up the glycation process.

Physician's Insight

"We know that moisturisers help replenish the lipids around the skin, keep the skin supple and hydrated."

Dr. Wassim Taktouk

Cosmetic Doctor

Dr. Wassim Taktouk

Cosmetic Doctor

Key Ingredients

Drying Alcohol-Free

👁

18% Concentrated Proxylane

Helps support skin’s integrity and correct visible signs of Ageing, like wrinkles and laxity.

4.25% Wild Fruit Flavonoids

Combination of blueberry and pomegranate extracts help reduce oxidative stresCB3:CD3s, which can be linked to A.G.E. formation, and protect against free radical damage.

0.1% Glycyrrhetinic Acid

Helps counter dull tone, which can be linked to A.G.E. accumulation, and is known for its soothing properties.

3% Hepes

Activates natural enzymes in skin to promote even cell turnover while hydrating skin.

1% Niacinamide

Water-soluble vitamin, also known as vitamin B3, soothes and helps support skin’s moisture barrier.

👁

How to Use A.G.E. Interrupter Advanced

Prep + Dispense

Twice daily, massage a thin, even layer of A.G.E. Interrupter Advanced wrinkle cream onto the entire face, neck, and chest.

Apply + Complete

If using in the morning, apply after a SkinCeuticals vitamin C antioxidant serum and before a SkinCeuticals sunscreen. If using with a retinol at night, apply after retinol application.

Answers to your frequently asked
A.G.E. Interrupter Advanced questions.

Like A.G.E. Interrupter, A.G.E. Interrupter Advanced is a wrinkle cream that fights glycation. A.G.E. Interrupter Advanced includes an increased concentration of Proxylane as well as additional efficacious ingredients in glycyrrhetinic acid HEPES that bring forth anti-glycation science and collagen decline reversal. The texture of A.G.E. Interrupter Advanced is the same as A.G.E. Interrupter, but the new formulation does have a different smell.

Glycation, a major factor of intrinsic and extrinsic Ageing, occurs when excess sugar molecules bind to collagen and elastin fibers and prompt the formation of advanced glycation end-products (A.G.E.). As a result, glycated collagen and elastin fibers lose the ability to function normally, and the body cannot break them down and replace them, leading to severe wrinkling of the skin.

Complete Your A.G.E. Interrupter Advanced Routine

Step 1: Prevent

AWARD WINNER

C E Ferulic For Visible Signs of Ageing

Vitamin C Antioxidant Serum For Normal & Dry Skin Types

One size

30 ml

Old price New price £165.00

(£550.00/100 ml.)

Step 2: Correct

Hyaluronic Acid Intensifier Multi-Glycan

New Formula

Hyaluronic Acid Intensifier Multi-Glycan

A hyaluronic acid volumising and plumping serum.

One size

30 ml

Old price New price £120.00

(£400.00/100 ml.)

Step 3: Correct

A.G.E. Interrupter Advanced For Ageing

Anti-wrinkle cream for Dry Skin

One size

48 ml

Old price New price £175.00

(£364.58/100 ml.)

Step 4: Protect

Ultra Facial Defense SPF 50+ Facial Sunscreen for Ageing and Discolouration-Prone Skin 30ml

A moisturising, daily-use sunscreen, helps prevent sun-induced discoloration and aging.

One size

30 ml

Old price New price £49.00

(£163.33/100 ml.)

Step 1: Prevent

Resveratrol B E Night Serum For Ageing Skin

Nightime Antioxidant Serum For Dry & Normal Skin Types

One size

30 ml

Old price New price £160.00

(£533.33/100 ml.)

Step 2: Correct

New Formula

Hyaluronic Acid Intensifier Multi-Glycan

A hyaluronic acid volumising and plumping serum.

One size

30 ml

Old price New price £120.00

(£400.00/100 ml.)

Step 3: Correct

A.G.E. Interrupter Advanced For Ageing

Anti-wrinkle cream for Dry Skin

One size

48 ml

Old price New price £175.00

(£364.58/100 ml.)

Step 4: Correct

A.G.E. Advanced Eye for Dark Circles & Wrinkles

NEW

A.G.E. Advanced Eye For Dark Circles

Eye cream suitable for Dry & Normal Skin

One size

15 ml

Old price New price £105.00

(£700.00/100 ml.)

Rated 3 out of 5 by Tiny_ from Nice textured cream but heavily scented! It is a lovely balmy cream that’s nourishing. I have very dry skin and I tend to use this at night after retinol. I’ve been using it for two weeks and I think there’s a slight improvement in the way my skin looks overall. But the reason I give it only 3 stars is because it’s heavily perfumed. It’s such a let down due to that for the sensitive skin types. If it was fragrance free it would be 5 stars. Sadly I won’t be repurchasing as the scent is far too strong and lingers for hours even stays on the bedding. If you like fragrance in your skincare then you’ll probably enjoy it.

Date published: 2025-02-06

Rated 1 out of 5 by Joy C from Great product shocking service Great product shocking service Emailed them 4 times and still no response but inundated with surveys.

Date published: 2024-12-20

Rated 1 out of 5 by Amy29 from Severe Reaction and Zero Support! I purchased this product together with the Brighten and Hydrate set with high hopes, but it ended up being one of the worst skincare experiences I’ve ever had. After using the product, I developed a severe, full-face reaction that has lasted over two weeks. My skin became inflamed, irritated, and painful, leaving me with acne scars that I’m now struggling to fade. Not only did this product cause visible damage, but it also took a toll on my confidence and well-being during this time. To make matters worse, I reached out to the customer service team, hoping they’d assist with a solution or offer some form of compensation. After missing their initial call, I assumed they’d try again or follow up via email, but I haven’t heard from them since. This lack of responsiveness has only added to my stress and disappointment. I expected better support, especially from a company that promotes its products as gentle and safe. I truly hope others consider this experience before purchasing, as I would never want anyone else to go through the physical and emotional distress that this product has caused me.

Date published: 2024-11-03

Rated 5 out of 5 by Trish from Lovely cream ! Beautiful cream, glides on and absorbs well ., my skin seems to love it , and I have seen improvement in my neck area in just a few weeks , just need to use sparingly as its quite expensive .

Date published: 2024-08-28

Rated 5 out of 5 by Maris2023 from A powerful serum Since I started using this powerful serum my skin surface appears smother and firmed. The product is an advanced anti ageing that control the loss of firmness ,target visible fine lines and restore the skin elasticity. I am using it before going to sleep in order to enhance the skin radiance while resting properly .

Date published: 2024-08-27

Rated 1 out of 5 by Kate L from Waxy and doesn’t absorb into skin Bought many products from this brand to try and this cream is most disappointing. It is thick, waxy and just does not absorb into my skin at all, my skin still feel dry, not hydrated after use. I’ve just turned 40 and have combination skin, this cream is one of the worse creams in the market for aging skin. Do not recommend at all. Their 242 and b5 are much better.

Date published: 2024-08-26

Rated 5 out of 5 by Happy 1961 from A.G.E interrupter advanced cream I have chronic dry sensitive skin…red,blotch.flaky the lot…this cream is like a dream from heaven…my skin looks moist healthy and I smile at myself when I look in the mirror instead of sad …I’m no beauty but this cream has made me feel not only normal but mentally happy with myself…it’s expensive but worth it…I’m going to save to treat myself to these amazing products…highly recommend…thank you Skinceuticals …

Date published: 2024-08-07

Rated 5 out of 5 by Maris2023 from A fabulous anti ageing advanced product This skincare product has great results . Integrated in my anti ageing routine in order to fight the appearance of my mature skin , this advanced multi correction treatment has improved the signs of ageing while deeply hydrating my skin .I love it as it is comfortable to wear and make my skin soft and firmed!

Date published: 2024-08-01

A.G.E. Interrupter Advanced Reviews - page 2

A.G.E. Interrupter Advanced For Ageing

A.G.E. Interrupter Advanced Benefits

Anti-wrinkle cream for Dry Skin

SCIENCE + PROOF

Visible Results

Visible Results

The Science Behind
A.G.E. Interrupter Advanced For Ageing

What is Skin Glycation?

Glycation Dos and Don’ts