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Advanced RGN-6

Skin rejuvenation cream
Advanced RGN-6 is rated 4.7 out of 5 by 282.
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Advanced RGN-6 is a skin rejuvenation cream, ideal for both daily and post-treatment use, this paten ... Read more

Advanced RGN-6
Advanced RGN-6
Advanced RGN-6
Advanced RGN-6
Advanced RGN-6
Advanced RGN-6
Advanced RGN-6
Advanced RGN-6
Advanced RGN-6
Advanced RGN-6

RECOMMENDED FOR

• Normal
• Oily


• Dry
• Combination

• Sensitive
• Aging

Advanced RGN-6

Skin rejuvenation cream

One size only
Selected 50 ml
Old price New price £160.00
, 1 of 1
Great news! Enjoy a FREE delivery on your order!
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PDP Product Benefits Section


Advanced RGN-6 Benefits

Benefits Icons

Reverse visible ageing damage

Benefits Icons

Reduces damage-induced pigmentation, and wrinkles

Benefits Icons

Visibly reduces stubborn discoloration by -23%

Benefits Icons

Minimises laser downtime and complements the outcome*

Benefits Icons

1.8x better skin barrier recovery***

Benefits Icons

Suitable for daily and post-laser use*

Benefits Icons

Fragrance-free, alcohol-free

Benefits Icons

Ideal for all skin types, even sensitive skin



PDP Product Details Section

Product Benefits

Skin rejuvenation cream

Advanced RGN-6 is a comforting, non-greasy cream that uses biomimetic technology to act as a “second skin” for 1.8x better barrier recovery*. Tested with ablative and non-ablative lasers, Advanced RGN-6 helps complement the outcome and reduce treatment downtime and PIH**. It is free of fragrance and alcohol – making it suitable for sensitive skin.

Advanced RGN-6 is a skin rejuvenation cream, ideal for both daily and post-treatment use, this patented formula is powered by 6 core ingredients to activate the skin repair process and help reverse signs of ageing, like stubborn discoloration, and wrinkles for a visibly rejuvenated appearance.

*after 1 hr. vs. untreated skin
** *If you are considering an aesthetic treatment, always consult a Medical Professional. Advance RGN-6 is a cosmetic skincare product for topical use. Only apply on healed skin.

Advanced RGN-6 is a skin rejuvenation cream, ideal for both daily and post-treatment use, this patented formula is powered by 6 core ingredients to activate the skin repair process and help reverse signs of ageing, like stubborn discoloration, and wrinkles for a visibly rejuvenated appearance.

*after 1 hr. vs. untreated skin
** *If you are considering an aesthetic treatment, always consult a Medical Professional. Advance RGN-6 is a cosmetic skincare product for topical use. Only apply on healed skin.

HOW TO USE >

   FAQS >



PDP Before After Section

Advanced RGN-6
SCIENCE + PROOF



Visible Results

POWERFUL WHEN USED ALONE

In a clinical study, Advanced RGN-6 significantly improved the appearance of key indicators of daily damage:

  • 36% Reduction in damage-induced pigmentation
  • 35% Increase in smoothness
  • 35% Increase in elasticity
  • 35% Increase in firmness
  • 18% Reduction in wrinkles
  • 17% Reduction in pores

POWERFUL WHEN USED POST-TREATMENT

​In a non-ablative laser study, Advanced RGN-6 demonstrated its​ ability to complement treatment outcomes and minimise downtime*.

👁 SEE OUR PROTOCOL



35%

Increase in
firmness

36%

Reduction in
damage-induced pigmentation

18%

Reduction in
wrinkles


Visible Results

POWERFUL WHEN USED ALONE

In a clinical study, Advanced RGN-6 significantly improved the appearance of key indicators of daily damage:

  • 36% Reduction in damage-induced pigmentation
  • 35% Increase in smoothness
  • 35% Increase in elasticity
  • 35% Increase in firmness
  • 18% Reduction in wrinkles
  • 17% Reduction in pores

POWERFUL WHEN USED POST-TREATMENT

​In a non-ablative laser study, Advanced RGN-6 demonstrated its​ ability to complement treatment outcomes and minimise downtime*.

35%

 

Increase in
firmness


36%

 

Reduction in
damage-induced pigmentation


18%

 

Reduction in
wrinkles


👁 SEE OUR PROTOCOL
PDP Product The Science Behind


The Science Behind
Advanced RGN-6


 
PDP Product Hero Banner
PHYSICIAN INSIGHT
PDP Product Ingredients Section

Key Ingredients


An icon representing a laboratory flask inside a circle with a diagonal line crossing it, indicating "no" or prohibition related to laboratory activities.

Paraben-Free

An icon of a droplet with "0%" written inside, indicating no water content.

Alcohol-Free

Icon of a dropper with a drop of liquid, enclosed in a crossed-out circle, indicating no dropping or dispensing.

Fragrance-Free

An illustration of a pipette with a drop of liquid, enclosed in a circle with a diagonal line crossing it, indicating "no pipettes" or "no droppers."

Dye-Free


👁

2% Niacinamide

10% Glyco-Repair™

A nutrient-dense derivative of carob seeds, glyco-repair™ helps to trigger barrier repair and renew skin texture.



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2% Niacinamide

1% Eperuline

Derived from eperua falcata bark, eperuline has been shown to soothe skin, reduce signs of aging, and combat laser-induced oxidative stress.



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Abstract close-up of a textured icy surface, highlighting intricate patterns and shapes formed by frost and ice.

2% Niacinamide

Also known as vitamin B3, this water-soluble vitamin is found naturally in yeast, meat, fish, milk, eggs, green vegetables, beans, and cereal grains. It has been shown to help reduce the appearance of skin discoloration.



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Abstract image of iridescent colors and swirling patterns, resembling delicate layers of a soap bubble.

3% Acetyl Tetrapeptide-9

A powerful signal peptide, acetyl tetra-peptide 9 helps support skin's structure and integrity for firmer, more resilient skin.



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Ectoin

0.2% Ectoin

An amino acid derivative and extremolyte (molecule that helps stabilize and protect organisms under extreme conditions), ectoin helps prevent oxidative damage and discoloration.


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A close-up of yellow liquid flowing with bubbles, creating smooth, wavy patterns.

0.2% Bioceramide 603

A patented, exclusive ceramide analog, bioceramide-603 is shown to target discoloration and post-treatment redness.


READ MORE >


    👁
    PDP Product How to Use Section

    How to Use Advanced RGN-6

    1

    Prep + Dispense

    Once or twice daily after cleansing, apply 1-2 pumps of Advanced RGN-6 to the palm of the hand and press into the skin of the forehead cheeks and chin.



    2

    Apply + Complete

    Blend the product into the skin. If using in the morning, apply after a SkinCeuticals vitamin C antioxidant serum and before a SkinCeuticals sunscreen.


    PDP FAQs Section
     
    FAQ



    Answers to your frequently asked
    Advanced RGN-6 questions.



     
    PDP Complete Your Regimen Section

    Complete Your Advanced RGN-6 Routine

    Step 1: Prevent

    C E Ferulic Vitamin C Antioxidant Serum
    C E Ferulic Vitamin C Antioxidant Serum
    C E Ferulic Vitamin C Antioxidant Serum
    C E Ferulic Vitamin C Antioxidant Serum
    AWARD WINNER

    C E Ferulic For Visible Signs of Ageing

    Vitamin C Antioxidant Serum For Normal & Dry Skin Types

    One size
    30 ml
    Old price New price £169.00

    Step 2: Correct

    Hyaluronic Acid Intensifier Multi-Glycan
    Hyaluronic Acid Intensifier Multi-Glycan
    Hyaluronic Acid Intensifier Multi-Glycan
    Hyaluronic Acid Intensifier Multi-Glycan
    New Formula

    Hyaluronic Acid Intensifier Multi-Glycan

    A hyaluronic acid volumising and plumping serum.

    One size
    30 ml
    Old price New price £120.00

    Step 3: Correct

    Advanced RGN-6
    Advanced RGN-6
    Advanced RGN-6
    Advanced RGN-6

    Advanced RGN-6

    Skin rejuvenation cream

    One size
    50 ml
    Old price New price £160.00

    Step 4: Protect

    Ultra Facial Defense SPF 50+ Facial Sunscreen for Ageing and Discolouration-Prone Skin 30ml

    Ultra Facial Defense SPF 50+ Facial Sunscreen for Ageing and Discolouration-Prone Skin 30ml

    A moisturising, daily-use sunscreen, helps prevent sun-induced discoloration and aging.

    One size
    30 ml
    Old price New price £50.00
      Great news! Enjoy a FREE delivery on your order!
      PDP Product Integrated Skincare Section

      Pair Your In-Office Treatments with
      At-Home Products


      DISCOVER NOW

      In-Office

      +

      At-Home

      Integrated Skincare

      Non-Ablative Laser >

      Integrated Skincare

      Advanced RGN-6

      Integrated Skincare

      Ablative Laser >

      Integrated Skincare

      Advanced RGN-7

         
        PDP Reviews
        Rated 5 out of 5 by from Crème Réparatrice très efficace 🥰 [Cet avis a été recueilli en réponse à une offre.] J’ai testé le SkinCeuticals Advanced RGN-6 pendant quelques jours et franchement c’est un produit assez agréable à utiliser au quotidien. Le format est simple et pratique, ça s’intègre facilement dans une routine sans y penser. Sur la peau, il est vraiment léger, ne colle pas et ne laisse pas de fini gras, ce que j’ai bien apprécié surtout le matin. Niveau résultats, même en peu de temps j’ai trouvé ma peau un peu plus lisse et avec un meilleur éclat, ça reste subtil mais ça se voit. Le packaging est discret et solide, rien de gênant à signaler. Globalement, une bonne surprise, surtout si on cherche quelque chose d’efficace sans être trop lourd.
        Date published: 2026-04-08
        Rated 5 out of 5 by from Excellent résultat Très bon produit intégré dans une routine matin et soir avec d'autres produits de la même marque
        Date published: 2026-03-20
        Rated 5 out of 5 by from Great for texture and fine lines I've been using this morning and evening for several weeks now, and it's made a real difference to the texture of my skin. I'm really self-conscious about the 'eleven' lines between my eyebrows and they now look less deep. My pores also appear smaller and the fine lines on the tops of my cheeks are softer. It absorbs super quickly , feels comfortable on skin and doesn't pill under make-up, even when I layer sunscreen on top. I'm really happy with the results so far and can't wait to see how my skin continues to improve as I keep using it.
        Date published: 2026-01-09
        Rated 5 out of 5 by from Powerful I liked the look and feel of this product on my face. The cream has visibly improved the skins texture, leaving it feeling smooth, youthful and radiant. The early laughter lines on the face appear faded, and my skin looks healthy even in this cold weather. The consistency of the cream is just right, not too thick or thin. It’s a good product.
        Date published: 2026-01-09
        Rated 5 out of 5 by from Skin ceuticals Advanced RGN-6 Skin Ceuticals RGN-6 is the best cream I have used! It actually really works! I use just 2 pumps of cream applied to my face and neck twice daily, morning and night. There are visible results after just one week of use. The wrinkles around my eyes are less prominent and wrinkles on my forehead have completely disappeared! Will definitely be buying once I’ve ran out.
        Date published: 2026-01-09
        Rated 5 out of 5 by from Great product Really good product and you can see results after a short time of using which is always a bonus. The smell and texture of the product are great too.
        Date published: 2026-01-09
        Rated 4 out of 5 by from Would recommend I love that this cream feels lightweight on my skin yet helps tackle and repair many anti-ageing concerns. It looks to reduce and reverse pigmentation, wrinkles and pores as well as smooth the skin and strengthen the skin barrier. It uses patented technology with six core ingredients including Niacinamide and Glyco-Repair. After using this cream, I felt my skin feel smoother, firmer and look brighter. My skin looks more fresh as a result. The cream didn't feel sticky or greasy on my skin. It is fragrance free. I apply this morning and night to my face and neck, ensuring a thin layer is applied. I love that as a result, a little goes a long way with this product!
        Date published: 2026-01-09
        Rated 4 out of 5 by from Great texture and positive results Comforting non greasy cream that strengthens the skin barrier, calms sensitive areas and I found it tones and firmed fine lines too
        Date published: 2026-01-08
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