A.G.E. Interrupter Advanced For Ageing

Anti-wrinkle cream for Dry Skin

A.G.E. Interrupter Advanced is rated 4.4 out of 5 by 168.

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A.G.E. Interrupter Advanced is a potent corrective cream that helps reverse visible signs of ageing ... Read more

RECOMMENDED FOR

• Dry

• Normal

• Combination

• Sensitive

• Ageing

A.G.E. Interrupter Advanced For Ageing

Anti-wrinkle cream for Dry Skin

Old price New price £175.00 (£3,645.83/L.)

48 ml

Old price New price £175.00

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A.G.E. Interrupter Advanced Benefits

Helps address the multi-phase glycation
process known to visibly age skin

Smooths an extended range of visible wrinkle types, including fine lines, deep wrinkles, and location-specific creases like nasolabial folds

Helps restore skins firmness and elasticity, which is known to decline as glycation degrades skin's collagen

Enhances skin's overall radiance, improves tone, and reduces blotchiness for a healthier-looking complexion

Delivers rich hydration, with a luxurious,
satin finish

Free of parabens, drying alcohol, and dyes

Anti-wrinkle cream for Dry Skin

Discover A.G.E Interrupter Advanced an anti-ageing cream that targets visible ageing, which helps improves the appearance of wrinkling and restores the skin's firmness

A.G.E. Interrupter Advanced is a potent corrective cream that helps reverse visible signs of ageing impacted by collagen decline and glycation, including wrinkling, laxity, and dullness. This next-generation anti-wrinkle cream is formulated with 18% concentrated Proxylane (+20% more than previous A.G.E. Interrupter ), 4.25% wild fruit flavonoid blend (12.5% more), and new 0.1% glycyrrhetinic acid. This advanced technology is clinically shown to help improve the appearance of wrinkles, help restore the skin's firmness, and enhance skin's radiance. *Due to the formulas high levels of flavonoids, this cream's colour may vary but will remain effective.

HOW TO USE >

FAQS >

SCIENCE + PROOF

Visible Results

Interrupter Advanced improved attributes associated with skin ageing and glycation, including lines and deep wrinkles in five facial zones.

Protocol: A 12-week, single-center, clinical study was conducted on 77 females with Fitzpatrick type I-VI, ages 35-75, and mild to moderate global wrinkles, fine lines, laxity, rough skin texture, uneven skin tone, and a dull complexion. A.G.E. Interrupter Advanced was used twice daily over face, neck, and chest in conjunction with a sunscreen for 12 weeks. Efficacy and tolerance evaluations were conducted at baseline, weeks 4, 8, and 12.

Close-up of a forehead and eyebrows, showcasing the skin texture and hair before a cosmetic treatment.

Visible Results

The Science Behind
A.G.E. Interrupter Advanced For Ageing

What is Skin Glycation?

Glycation is natural process that accelerates visible signs of Ageing. During the glycation process, excess sugars bind to skin-supporting proteins (like collagen and elastin) and form advanced glycation end-products (A.G.E.s). A.G.E.s weaken collagen, leading to wrinkles and laxity.

Signs of Glycation
1. Wrinkling and crepiness
2. Loss of firmness
3. Dull, sallow complexion

Glycation Dos and Don’ts

DO: Wear Sunscreen
Protect skin from UV damage (add a link https://www.skinceuticals.co.uk/en_GB/suncare) and oxidative stress by applying broad-spectrum sunscreen daily.

DO: Reduce Sugar
Alcohol consumption and high-sugar diets can promote the glycation process. HEADER 3: DON’T: Expose Skin to SmokeCOPY 3: Cigarette smoke deposits a myriad of chemicals onto the skin in addition to speeding up the glycation process.

Physician's Insight

"We know that moisturisers help replenish the lipids around the skin, keep the skin supple and hydrated."

Dr. Wassim Taktouk

Cosmetic Doctor

Dr. Wassim Taktouk

Cosmetic Doctor

Key Ingredients

Drying Alcohol-Free

👁

18% Concentrated Proxylane

Helps support skin’s integrity and correct visible signs of Ageing, like wrinkles and laxity.

4.25% Wild Fruit Flavonoids

Combination of blueberry and pomegranate extracts help reduce oxidative stresCB3:CD3s, which can be linked to A.G.E. formation, and protect against free radical damage.

0.1% Glycyrrhetinic Acid

Helps counter dull tone, which can be linked to A.G.E. accumulation, and is known for its soothing properties.

3% Hepes

Activates natural enzymes in skin to promote even cell turnover while hydrating skin.

Abstract close-up of a textured, light-colored surface with undulating lines and shapes, creating a fluid appearance.

1% Niacinamide

Water-soluble vitamin, also known as vitamin B3, soothes and helps support skin’s moisture barrier.

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How to Use A.G.E. Interrupter Advanced

Prep + Dispense

Twice daily, massage a thin, even layer of A.G.E. Interrupter Advanced wrinkle cream onto the entire face, neck, and chest.

Apply + Complete

If using in the morning, apply after a SkinCeuticals vitamin C antioxidant serum and before a SkinCeuticals sunscreen. If using with a retinol at night, apply after retinol application.

Answers to your frequently asked
A.G.E. Interrupter Advanced questions.

Like A.G.E. Interrupter, A.G.E. Interrupter Advanced is a wrinkle cream that fights glycation. A.G.E. Interrupter Advanced includes an increased concentration of Proxylane as well as additional efficacious ingredients in glycyrrhetinic acid HEPES that bring forth anti-glycation science and collagen decline reversal. The texture of A.G.E. Interrupter Advanced is the same as A.G.E. Interrupter, but the new formulation does have a different smell.

Glycation, a major factor of intrinsic and extrinsic Ageing, occurs when excess sugar molecules bind to collagen and elastin fibers and prompt the formation of advanced glycation end-products (A.G.E.). As a result, glycated collagen and elastin fibers lose the ability to function normally, and the body cannot break them down and replace them, leading to severe wrinkling of the skin.

Complete Your A.G.E. Interrupter Advanced Routine

Step 1: Prevent

AWARD WINNER

C E Ferulic For Visible Signs of Ageing

Vitamin C Antioxidant Serum For Normal & Dry Skin Types

One size

30ml

Old price New price £169.00

(£5,633.33/L.)

Step 2: Correct

Hyaluronic Acid Intensifier Multi-Glycan

New Formula

Hyaluronic Acid Intensifier Multi-Glycan

A hyaluronic acid volumising and plumping serum.

One size

30 ml

Old price New price £120.00

(£4,000.00/L.)

Step 3: Correct

A.G.E. Interrupter Advanced For Ageing

Anti-wrinkle cream for Dry Skin

One size

48 ml

Old price New price £175.00

(£3,645.83/L.)

Step 4: Protect

Ultra Facial Defense SPF 50+ Facial Sunscreen for Ageing and Discolouration-Prone Skin 30ml

A moisturising, daily-use sunscreen, helps prevent sun-induced discoloration and aging.

One size

30ml

Old price New price £50.00

(£1,666.67/L.)

Step 1: Prevent

Resveratrol B E Night Serum For Ageing Skin

Nightime Antioxidant Serum For Dry & Normal Skin Types

One size

30ml

Old price New price £164.00

(£5,466.67/L.)

Step 2: Correct

New Formula

Hyaluronic Acid Intensifier Multi-Glycan

A hyaluronic acid volumising and plumping serum.

One size

30 ml

Old price New price £120.00

(£4,000.00/L.)

Step 3: Correct

A.G.E. Interrupter Advanced For Ageing

Anti-wrinkle cream for Dry Skin

One size

48 ml

Old price New price £175.00

(£3,645.83/L.)

Step 4: Correct

A.G.E. Advanced Eye for Dark Circles & Wrinkles

Best Seller

A.G.E. Advanced Eye For Dark Circles

Eye cream suitable for Dry & Normal Skin

One size

15 ml

Old price New price £109.00

(£7,266.67/L.)

Rated 3 out of 5 by shay from any recent UK reviews ? Not a product review - but curious as to why the most recent reviews seem to be in French ? And the UK ones seem to be from a year ago ?

Date published: 2026-07-15

Rated 5 out of 5 by Gehan from Complexion looks healthier My skin feels comfortable and fresh and calm and no irritation

Date published: 2025-11-25

Rated 5 out of 5 by Sue D from The best moisturiser! This product is like applying silk to my skin. I just love it 😍

Date published: 2025-11-20

Rated 1 out of 5 by Roara C from Eye cream is a yes, skin cream is a no. The eye cream is fantastic, it helps to take skin that was leathery and bring it to life. The the skin cream is very waxy and tacky and I’m not sure how anyone wears this isn’t make up. The eye cream again is fantastic. I use this cream now as a masque for a few hours, then take it off, or use it at night, the eye cream inside anytime. Skincueticals need better direction on product layering. I’m about to go to another brand that gives clear direction even though available online it’s clear what to Sue when, half the time I’m guessing. There’s a salon near me and even the. It’s not clear what to use when.

Date published: 2025-10-26

Rated 5 out of 5 by Wot123 from Best moisturiser I have ever tried! I rarely write reviews but wow, this moisturiser is amazing!! It should be for the money mind you. It glides on and is so moisturising without being greasy. I have really noticed a difference on my skin and I am combining it with the CE ferulic and multiglycan products. My only disappointment is that I am using it up quicker than I hoped!

Date published: 2025-09-26

Rated 5 out of 5 by Sharon62 from Outstanding moisturiser I have been buying this product for about 2 years. I’m in my 60’s and travel quite a lot to countries with varying climates. This cream moistens without leaving a residue. It is not too heavy for hot countries. You don’t need a lot per application. My skin feels nutrified and plumper. It works well with the pre layering serums.

Date published: 2025-06-09

Rated 1 out of 5 by Lakey from Terrible cream Terrible cream,does not absorb in to skin,very thick and does not do one thing for your skin.

Date published: 2025-05-02

Rated 3 out of 5 by Tiny_ from Nice textured cream but heavily scented! It is a lovely balmy cream that’s nourishing. I have very dry skin and I tend to use this at night after retinol. I’ve been using it for two weeks and I think there’s a slight improvement in the way my skin looks overall. But the reason I give it only 3 stars is because it’s heavily perfumed. It’s such a let down due to that for the sensitive skin types. If it was fragrance free it would be 5 stars. Sadly I won’t be repurchasing as the scent is far too strong and lingers for hours even stays on the bedding. If you like fragrance in your skincare then you’ll probably enjoy it.

Date published: 2025-02-06

A.G.E. Interrupter Advanced Reviews - page 2

A.G.E. Interrupter Advanced For Ageing

A.G.E. Interrupter Advanced Benefits

Anti-wrinkle cream for Dry Skin

SCIENCE + PROOF

Visible Results

Visible Results

The Science Behind
A.G.E. Interrupter Advanced For Ageing

What is Skin Glycation?

Glycation Dos and Don’ts