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Discoloration Defense Serum

High-potency serum targets visible skin discolouration for brighter, more even-looking skin
Discoloration Defense Serum is rated 4.3 out of 5 by 76.
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Discoloration Defense Serum is layerable, daily-use dark spot corrector serum clinically proven the ... Read full description

Discoloration Defense Serum

Discoloration Defense Serum

High-potency serum targets visible skin discolouration for brighter, more even-looking skin

Why shop with us ?

  • Free delivery on all orders​
  • 2 free luxury samples on every order worth up to £38
  • Free Next Day Delivery with all orders over £200*

Discoloration Defense Serum is layerable, daily-use dark spot corrector serum clinically proven the reduce the appearance of key types of skin discolouration, including stubborn brown patches and post-blemish scars. Our latest generation formula improves the appearance of skin discolouration to reveal visibly brighter- looking skin.

SKIN TYPES: Normal, Oily, Combination, Dry

SKIN CONDITION: Discolouration

Key Ingredients

1.8% Tranexamic Acid

5% Niacinamide

5% Hepes



*Please be aware that ingredient lists for products in our brand are updated regularly. Please refer to the ingredient list on the product package for the most up-to-date list of ingredients to ensure it is suitable for your personal use.

Discoloration Defense Serum

How is SkinCeuticals committed to becoming more sustainable?

SkinCeuticals is committed to looking for ways to improve the sustainability profile of our formulas and ingredient development by aiming to follow these principles:

  • Reduce our water footprint index
  • Source more renewable ingredients
  • Increase biodegradability (of rinse-off formulas)
  • Minimise our packaging through continuous optimisation and innovation and greater use of post-consumer recycled (PCR) materials.

Features a synergistic blend of anti-discolouration and exfoliating ingredients to improve the appearance of skin discoloration including hyperpigmentation, post-blemish scars and stubborn brown spots.

Ideal at-home complement to professional skin discolouration treatments, such as chemical peels or non-ablative laser; always consult with a physician for individual regimen recommendations

Discoloration Defense Serum

How to Use

  • Twice daily, apply 3-5 drops of Discoloration Defense serum to the face and neck
  • If using in the morning, apply after a SkinCeuticals vitamin C serum and follow with a SkinCeuticals broad spectrum SPF 30+ sunscreen
  • Limit sun exposure while using this product

1. Cleanse & Tone

Cleanse and tone the skin. Pat dry.

We recommend
Gentle Cleanser

2. Prevent

Apply 4-5 drops of your anitoxidant seurm to a dry face, neck, and chest.

We recommend
Phloretin CF

3. Correct

Apply  3-5 drops of Discoloration Defense serum to the face and neck. Always follow with a sunscreen. 

We recommend
Discoloration Defense Serum & Advanced Brightening UV Defense

Clinical Results

Individual results at 12 weeks.

Before and after results

Protocol: 12-week, clinical study, 63 subjects. Discoloration Defense Serum was applied to the face twice a day in conjunction with a sunscreen. 

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Rated 5 out of 5 by from Great Serum I have been using this serum now for 3 weeks. It’s not an overnight cure, no product can do that, but I have noticed a reduction in the intensity of my discolouration. I have areas on my cheek and forehead which are always worse in summer anyway. I think with continued use this will definitely help even out the skin tone and stop new areas of discolouration forming. It’s a lovely serum to use, it’s hydrating and gives a nice subtle glow to the skin. I use good skin care anyway but noticed a clearer complexion since using this product. Definitely will be adding this to my skin care arsenal.
Date published: 2019-08-29
Rated 3 out of 5 by from Interesting product I have been using this serum now for 4 weeks. The serum is slightly sticky on the skin but after absorbtion and use of moisturiser is not so bad. I have a few discoloured spots on my cheeks an a couple on my forehead and do feel that they have paled very slightly but not significantly enough to notice unless under close scrutiny. However I am hoping that with continued use I will see a diffirence. I am a great believer that the older your skin is the longer a product takes to work.My hope is that it will stop further discolouration. Will review again in a further 4 weeks if results change.
Date published: 2019-08-26
Rated 4 out of 5 by from Clarity I received this product 2 weeks ago I have suffered with malsama for 8 years now and I have tried every product available for this condition some help but as soon as I go in the sun it creeps back so I have to wear factor 50 even on rainy days. I found this product even after 1 weeks made my skin look clearer and brighter so if its this good after that short time I've high Hope's for a few months the consistency is also great skin feels hydrated
Date published: 2019-08-19
Rated 2 out of 5 by from Didn't seem to make any difference I've used this once or twice a day for about a month now, and unfortunately I haven't seen any difference in my skin at all. I have a few dark acne scars and sun spots, but they're still just the same as always. I'm surprised as pretty much every other Skinceuticals product I've tried has worked really well.
Date published: 2019-11-12
Rated 4 out of 5 by from Great texture The texture of this is really refined; it’s not gritty in any way as cheaper niacinamide products I’ve tried have been and it has caused no irritation. I found that the colour of a cystic spot I had at the time of testing disappeared quickly so it appears to work well at reducing pigmentation, although I can’t speak to anything like melasma. I will continue to use it as I hope that the niacinamide content will help to redness and pore size too over time.
Date published: 2019-08-24
Rated 3 out of 5 by from Good texture, don't expect miracles The texture is good, light and absorbed quickly. You really do just need 4-5 drops as advised, any more and it drys a bit tacky. There is no scent. It goes on nicely as the 1st or 2nd step in getting my face ready with the final step being suncare. I mainly used it at night and in the morning there is a mild noticeable even tone about my skin. This is with two weeks use. But I am also using Phloretin and have had a mandelic peel at the start of the 2 weeks. Perhaps over time, the discolouration changes will be more noticeable.
Date published: 2019-08-25
Rated 3 out of 5 by from Not sure..... Only had a week to test this and I wish I could have had a little longer. I can't see any change in discolouration, it all still looks the same.... Also, can't make my mind up about the serum. It's a very light liquid and you only need a couple of drops, but when put on to the skin, it felt quite sticky and when I put on a moisturiser, it sometimes felt too sticky, not really happy about this. Also, during the day, my face would feel quite dry and I would have to add more moisturiser. Apart from the above, face did look a little brighter.....
Date published: 2019-08-19
Rated 5 out of 5 by from It really works! I noticed a difference in the first few days of using this serum which I was sent to review. There was a definite brightness to the skin and clarity. It has helped to even my skin tone giving it radiance. I noticed that a few age spots have started to lighten already. I think using this product over a period of time will produce even better results. The serum itself caused no irritation to my skin and was easy to apply. It is definitely a serum I will now carry on using as the results were noticeable quickly. Fully worth 5 star rating.
Date published: 2019-08-24
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