AWARD WINNER

Discoloration Defense For Skin Discoloration

Skin Discoloration + Dark Spot Serum For Dry & Oily Skin

Discoloration Defense Serum is rated 4.2 out of 5 by 135.

Discoloration Defense is a layerable, daily-use dark spot corrector proven to reduce the appearance ... Read more

AWARD WINNER

RECOMMENDED FOR

• Dry

• Normal

• Oily

• Combination

• Skin Discolouration

SkinCeuticals

Discoloration Defense For Skin Discoloration

Skin Discoloration + Dark Spot Serum For Dry & Oily Skin

30 ml

Old price New price £110.00

Quantity

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Promotes even skin tone and reduce appearance of skin discolouration

Improves the appearance of stubborn brown patches

Improves the appearance of post-blemish marks

Fragrance-free

Skin Discoloration + Dark Spot Serum For Dry & Oily Skin

SkinCeuticals' Discoloration Defense Serum is a dark spot corrector that is clinically proven to reduce the appearance of skin discolouration

Discoloration Defense is a layerable, daily-use dark spot corrector proven to reduce the appearance of key types of skin discolouration. Formulated with 1,8% tranexamic acid, 5% niacinamide, and 5% HEPES, this formula serum for dark spots improves the appearance of skin discolouration, brightens skin, and evens skin tone.

HOW TO USE >

FAQS >

SCIENCE + PROOF

Visible Results

In a 12-week clinical study, Discoloration Defense significantly improved the appearance of key skin discoloration markers*

👁 SEE OUR PROTOCOL

60%

Average improvement in the appearance of stubborn brown patches

59%

Average improvement in the appearance of skin discoloration

81%

Average improvement in the appearance of post-acne marks

59%

Average improvement in the appearance of even skin tone

34%

Reduction in post-blemish marks at 12 weeks

Visible Results

In a 12-week clinical study, Discoloration Defense significantly improved the appearance of key skin discoloration markers*

In a new 12-week study on deeper skin tones (Fitzpatrick V-VI), twice-daily application of Discoloration Defense demonstrated a statistically-significant reduction in the appearance of discoloration, post-inflammatory discoloration, and even skin tone.**

60%

Average improvement in the appearance of stubborn brown patches

59%

Average improvement in the appearance of skin discoloration

81%

Average improvement in the appearance of post-acne marks

59%

Average improvement in the appearance of even skin tone

34%

Reduction in post-blemish marks at 12 weeks

👁 SEE OUR PROTOCOL

The Science Behind Discolouration Defense Serum

What is Skin Discolouration?

Skin discolouration is a result of excess melanin production due to exposure to environmental aggressors. Discolouration can appear in multiple ways, such as dark spots, redness, or post-acne marks. DiscolourationDefense can help to improve the appearance of dark spots, post-blemish marks, or uneven skin tone.

Skin Discolouration Dos + Don’ts

DO: Use Sunscreen Daily
To effectively help reduce and prevent discolouration and improve overall skin tone, always use a broad-spectrum SPF 30+ sunscreen.

DON’T: Skip Antioxidants
Exfoliate and brighten skin while correcting dark spots by incorporating an antioxidant-rich serum like discolourationDefense into your routine.

Expert's Insights

"SkinCeuticals Discoloration Defense contains Transexamic Acid which will help to manage the pigmentation cascade and helps to reduce active pigmentation and helps to prevent futher pigmentation."

Dr. Jonquille Chantrey

Aesthetic Doctor
ØNE aesthetic studiø

Dr. Jonquille Chantrey

Aesthetic Doctor
ØNE aesthetic studiø

Key Ingredients

Fragrance-Free

👁

1,8% Tranexamic Acid

This synthetically-derived ingredient minimizes the recurrence of skin discolouration and stubborn brown patches with continued use.

5% Niacinamide

Also known as vitamin B3, this water-soluble vitamin is found naturally in yeast, meat, fish, milk, eggs, green vegetables, beans, and cereal grains. It has been shown to help reduce the appearance of skin discolouration.

5% HEPES

This synthetically-derived exfoliant activates natural enzymes in the skin to help break the bonds that bind dead skin cells to the surface for even exfoliation.

How to Use Discoloration Defense Serum

Prep + Dispense

Twice daily, apply 3-5 drops of this skin discolouration serum to the face.

Apply + Complete

If using in the morning, apply after a SkinCeuticals vitamin C serum and follow with a SkinCeuticals broad spectrum SPF 30+ sunscreen. Limit sun exposure while using this product

* To discover which SkinCeuticals cosmetic skincare product is suitable for use with your aesthetic treatment, consult your practitioner. If you are considering an aesthetic treatment, always consult a Medical Professional. Only apply on healed skin.

** 8-week, single-centre clinical study was conducted on 78 females with Fitzpatrick type I-VI, ages 27-68, and mild to moderate wrinkles, fine lines, pore appearance, rough skin texture, clarity, dull complexion, clarity, discoloration. 40 subjects had mild-to-moderate acne marks/PIE/PIH. Cell Cycle Catalyst was applied once daily in the evening followed by a moisturizer. Efficacy and tolerance evaluations were conducted at baseline, week 1, week 4, and week 8.

*** 8-week split face study performed on 48 women, using their regular anti-ageing routine. Cell Cycle catalyst was applied on half of the face, with the other half left untreated.

****Self-assessment, 75 subjects

Answers to your frequently asked
Discolouration Defense questions.

Discolouration Defense should be used by applying 3-5 drops to the face twice daily. Morning applications of this serum for dark spots should be applied after SkinCeuticals vitamin C serum and before SkinCeuticals broad spectrum SPF 50+ sunscreen . Do not apply to broken or irritated skin. Sun exposure should also be limited while using this product.

Complete Your Discoloration Defense Routine

Step 1: Prevent

Phloretin CF Vitamin C Antioxidant Serum

AWARD WINNER

Phloretin CF Serum For Discolouration

Vitamin C Serum For Normal & Oily Skin Types

One size

30 ml

Old price New price £165.00

Step 2: Correct

AWARD WINNER

Discoloration Defense For Skin Discoloration

Skin Discoloration + Dark Spot Serum For Dry & Oily Skin

One size

30 ml

Old price New price £110.00

Step 3: Correct

Metacell Renewal B3

Daily emulsion reduces the appearance of discolouration and early signs of ageing.

One size

50 ml

Old price New price £122.00

Step 4: Protect

Advanced Brightening UV Defense SPF 50 for All Skin Types 40ml

Dual-action, lightweight sunscreen with SPF 50 that helps protect the skin from UV-induced discolouration and helps evens skin tone.

One size

40 ml

Old price New price £52.00

Step 1: Cleanse

Glycolic Renewal Cleanser

Soft-foaming gel cleanser exfoliates with a dual-acid blend while effectively cleansing impurities and long-wear makeup without stripping the skin of moisture.

One size

150 ml

Old price New price £45.00

Step 2: Correct

Resveratrol B E Night Serum For Ageing Skin

Nightime Antioxidant Serum For Dry & Normal Skin Types

One size

30 ml

Old price New price £160.00

Step 3: Correct

AWARD WINNER

Discoloration Defense For Skin Discoloration

Skin Discoloration + Dark Spot Serum For Dry & Oily Skin

One size

30 ml

Old price New price £110.00

Step 4: Correct

Metacell Renewal B3

Daily emulsion reduces the appearance of discolouration and early signs of ageing.

One size

50 ml

Old price New price £122.00

Rated 1 out of 5 by Wattboss from No result - Yet It might be too early to expect a change, but I've been usubg it every day for 2 weeks, and no difference whatsoever

Date published: 2025-03-17

Rated 1 out of 5 by Dr H Aziz from Comedogenic Each time I used it, acnes started to appear and then when I stopped using it, I was ok..I tested it 3 times and each time I started to use it, I broke out in painful acne. I was really looking forward to a clearer skin and instead ended up with blemishes

Date published: 2025-02-17

Rated 1 out of 5 by Sf16 from Waste of money Did absolutely nothing for my pigmentation, a waste

Date published: 2025-01-30

Rated 1 out of 5 by Sheau from SEVERE ALLERGY REACTIONS. NOT RECOMMENDED! Ordered their Discolouration Power Pair on Black Friday which included this serum. Woke up with red, itchy patches all over the face the next day after first use. The whole face was dry, flaky and bumpy. I felt a burning, stinging sensation whenever I wash my face. I have a combination skin and I've used many high end skincare products. This is the first time I've experienced allergic reactions. I've tried to contact the customer service via the contact form on this website, but 2 weeks has passed, and I've never heard from them. STRONGLY NOT RECOMMENDED TO OTHER USERS, even if you've never had any problems with skincare products, it doesn't mean Skinceuticals products are safe for you! Try it at your own risk because they won't entertain your enquiries if any allergic reactions occur!

Date published: 2024-12-20

Rated 5 out of 5 by LisaMarie from Goodbye dark spots Teams perfectly with my Phloretin cf and spf brightening. A great set of products. I am always looking to get on top of any discolouration after having melasma in the past. This is a brilliant product. I apply after my vitamin c and before my spf

Date published: 2024-08-26

Rated 1 out of 5 by JayDC from Made no difference I used the whole bottle which lasted a decent amount of time. I took ‘before’ photos before starting the product and ‘after’ photos once i had finished the bottle. I did not see a single change to my skin in the mirror from using this product. I went back and compared the ‘before’ photo and it confirmed my thoughts - this product did nothing for my uneven skin, nor did it brighten in any way. For the price i paid for this, it was a serious waste of my money and i cannot understand what this does to other people’s skin, that it failed to do to mine.

Date published: 2023-10-07

Rated 5 out of 5 by MissHolly from Skin looks great Worked amazing for my pigmentation <3 I wish I knew about this product before. Although it can take some time to see results it is worth persevering. My pigmentation has now faded so much and my skin tone is looking much more even all over.

Date published: 2022-11-09

Rated 4 out of 5 by Lexaev from No significant results I haven’t got any amazing results from this product. I have been using it for a few months now but wouldn’t say that it helped me with discolouration. I think sometimes it even caused more breakouts on the areas where I applied it. I still want to give another chance to this product, as I have seen good reviews. Will have a break from it and will try using it again soon.

Date published: 2022-06-14

Discoloration Defense Serum Reviews - page 2

Discoloration Defense For Skin Discoloration

Skin Discoloration + Dark Spot Serum For Dry & Oily Skin

SCIENCE + PROOF

Visible Results

60%

59%

81%

59%

34%

Visible Results

60%

59%

81%

59%

34%

The Science Behind Discolouration Defense Serum

What is Skin Discolouration?

Skin Discolouration Dos + Don’ts