Advanced RGN-6

Skin rejuvenation cream

Advanced RGN-6 is rated 4.7 out of 5 by 327.

Advanced RGN-6 is a skin rejuvenation cream, ideal for both daily and post-treatment use, this paten ... Read more

RECOMMENDED FOR

• Normal

• Oily

• Dry

• Combination

• Sensitive

• Aging

Advanced RGN-6

Skin rejuvenation cream

50 ml

Old price New price £160.00

Great news! Enjoy a FREE delivery on your order!

Quantity

Advanced RGN-6 Benefits

Reverse visible ageing damage

Reduces damage-induced pigmentation, and wrinkles

Visibly reduces stubborn discoloration by -23%

Minimises laser downtime and complements the outcome*

1.8x better skin barrier recovery***

Suitable for daily and post-laser use*

Fragrance-free, alcohol-free

Ideal for all skin types, even sensitive skin

Skin rejuvenation cream

Advanced RGN-6 is a comforting, non-greasy cream that uses biomimetic technology to act as a “second skin” for 1.8x better barrier recovery*. Tested with ablative and non-ablative lasers, Advanced RGN-6 helps complement the outcome and reduce treatment downtime and PIH**. It is free of fragrance and alcohol – making it suitable for sensitive skin.

Advanced RGN-6 is a skin rejuvenation cream, ideal for both daily and post-treatment use, this patented formula is powered by 6 core ingredients to activate the skin repair process and help reverse signs of ageing, like stubborn discoloration, and wrinkles for a visibly rejuvenated appearance.

*after 1 hr. vs. untreated skin
** *If you are considering an aesthetic treatment, always consult a Medical Professional. Advance RGN-6 is a cosmetic skincare product for topical use. Only apply on healed skin.

HOW TO USE >

FAQS >

Advanced RGN-6
SCIENCE + PROOF

Visible Results

POWERFUL WHEN USED ALONE

In a clinical study, Advanced RGN-6 significantly improved the appearance of key indicators of daily damage:

36% Reduction in damage-induced pigmentation
35% Increase in smoothness
35% Increase in elasticity
35% Increase in firmness
18% Reduction in wrinkles
17% Reduction in pores

POWERFUL WHEN USED POST-TREATMENT

In a non-ablative laser study, Advanced RGN-6 demonstrated its ability to complement treatment outcomes and minimise downtime*.

👁 SEE OUR PROTOCOL

35%

Increase in
firmness

36%

Reduction in
damage-induced pigmentation

18%

Reduction in
wrinkles

Visible Results

POWERFUL WHEN USED ALONE

In a clinical study, Advanced RGN-6 significantly improved the appearance of key indicators of daily damage:

36% Reduction in damage-induced pigmentation
35% Increase in smoothness
35% Increase in elasticity
35% Increase in firmness
18% Reduction in wrinkles
17% Reduction in pores

POWERFUL WHEN USED POST-TREATMENT

In a non-ablative laser study, Advanced RGN-6 demonstrated its ability to complement treatment outcomes and minimise downtime*.

35%

Increase in
firmness

36%

Reduction in
damage-induced pigmentation

18%

Reduction in
wrinkles

👁 SEE OUR PROTOCOL

The Science Behind
Advanced RGN-6

Visibly reverses 6 signs of ageing and tone damage

Using Advanced RGN-6, fine lines are visibly reduced, and skin is more refined, and it works to visibly reduce 6 signs of ageing and tone damage. Formulated with powerful ingredients like Glyco-Repair™, eperuline, and niacinamide, this skin rejuvenation cream helps promote barrier renewal, reduce visible signs of ageing, and soothe. Ectoin, acetyl tetrapetide-9, and bioceramide 603 aid in visible rejuvenation by enhancing surface renewal, increasing elasticity, and reducing discoloration.

Developed with Nearly 20 Skin Regeneration Experts

Advanced RGN-6 was developed in collaboration with nearly 20 scientists specialising in skin regeneration. Over 5 years of extensive research, 1000+ data points were generated to support the performance of its core engine of 6 ingredients on visible rejuvenation. Advanced RGN-6's exclusive technology holds three patents to promote barrier repair (FR 2972 110 A1), improve pigmentation (WO 2007/071875), and reduce post-treatment downtime (FR 2963 233 A1).

Advanced RGN-6 + Lasers

After laser treatment, skin is often sensitised and more vulnerable to stressors that can both slow recovery and impact the overall treatment result.

Advanced RGN-6 is a post laser treatment cream designed to complement results from laser treatments and minimise downtime*.
*If you are considering an aesthetic treatment, always consult a Medical Professional. Advance RGN-6 is a cosmetic skincare product for topical use. Only apply on healed skin.

Key Ingredients

Paraben-Free

Alcohol-Free

Fragrance-Free

Dye-Free

👁

10% Glyco-Repair™

A nutrient-dense derivative of carob seeds, glyco-repair™ helps to trigger barrier repair and renew skin texture.

1% Eperuline

Derived from eperua falcata bark, eperuline has been shown to soothe skin, reduce signs of aging, and combat laser-induced oxidative stress.

Abstract close-up of a textured icy surface, highlighting intricate patterns and shapes formed by frost and ice.

2% Niacinamide

Also known as vitamin B3, this water-soluble vitamin is found naturally in yeast, meat, fish, milk, eggs, green vegetables, beans, and cereal grains. It has been shown to help reduce the appearance of skin discoloration.

Abstract image of iridescent colors and swirling patterns, resembling delicate layers of a soap bubble.

3% Acetyl Tetrapeptide-9

A powerful signal peptide, acetyl tetra-peptide 9 helps support skin's structure and integrity for firmer, more resilient skin.

0.2% Ectoin

An amino acid derivative and extremolyte (molecule that helps stabilize and protect organisms under extreme conditions), ectoin helps prevent oxidative damage and discoloration.

A close-up of yellow liquid flowing with bubbles, creating smooth, wavy patterns.

0.2% Bioceramide 603

A patented, exclusive ceramide analog, bioceramide-603 is shown to target discoloration and post-treatment redness.

👁

How to Use Advanced RGN-6

1

Prep + Dispense

Once or twice daily after cleansing, apply 1-2 pumps of Advanced RGN-6 to the palm of the hand and press into the skin of the forehead cheeks and chin.

2

Apply + Complete

Blend the product into the skin. If using in the morning, apply after a SkinCeuticals vitamin C antioxidant serum and before a SkinCeuticals sunscreen.

Answers to your frequently asked
Advanced RGN-6 questions.

What does Advanced RGN-6 do?

Can Advanced RGN-6 be used every day?

How should I use Advanced RGN-6 post laser?

Advanced RGN-6 is a regenerating cream that can be used post-treatment to help soothe the skin and complement the outcome of laser. Following your treatment, apply Advanced RGN in the morning after Skinceuticals C E Ferulic^®, and Advanced RGN-6 again in the evening. For an added layer of protection a few days post-treatment, follow up Advanced RGN-6 with SkinCeuticals Ultra Facial UV Defence *If you are considering an aesthetic treatment, always consult a Medical Professional. Advance RGN-6 is a cosmetic skincare product for topical use. Only apply on healed skin

What benefits of laser does this improve?

Can I use Advanced RGN-6 with retinol?

Can I use Advanced RGN-6 with hyaluronic acid?

Can I use Advanced RGN-6 with vitamin C?

What colour is Advanced RGN-6 supposed to be?

Complete Your Advanced RGN-6 Routine

Step 1: Prevent

AWARD WINNER

C E Ferulic For Visible Signs of Ageing

Vitamin C Antioxidant Serum For Normal & Dry Skin Types

One size

30 ml

Old price New price £169.00

Step 2: Correct

Hyaluronic Acid Intensifier Multi-Glycan

New Formula

Hyaluronic Acid Intensifier Multi-Glycan

A hyaluronic acid volumising and plumping serum.

One size

30 ml

Old price New price £120.00

Step 3: Correct

Advanced RGN-6

Skin rejuvenation cream

One size

50 ml

Old price New price £160.00

Step 4: Protect

Ultra Facial Defense SPF 50+ Facial Sunscreen for Ageing and Discolouration-Prone Skin 30ml

A moisturising, daily-use sunscreen, helps prevent sun-induced discoloration and aging.

One size

30 ml

Old price New price £50.00

Great news! Enjoy a FREE delivery on your order!

Pair Your In-Office Treatments with
At-Home Products

DISCOVER NOW

In-Office

+

At-Home

Non-Ablative Laser >

Advanced RGN-6

Ablative Laser >

Advanced RGN-7

Rated 4 out of 5 by JulieR from Bon produit de soin [Cet avis a été recueilli en réponse à une offre.] J’ai beaucoup aimé utiliser cette crème. Sa texture fondante, donne un effet fraîcheur à la peau. J’ai senti ma peau visiblement hydratée et comme lissée. J’ai juste enlever une étoile par rapport à la composition notée médiocre car présence de phénoxyéthanol. Dommage car produit de qualité.

Date published: 2026-05-19

Rated 5 out of 5 by HarizS from J’adore [Cet avis a été recueilli en réponse à une offre.] J’utilise cette crème depuis quelques semaines et je suis très content. La texture est légère , pénètre rapidement sans laisser de film gras et la peau paraît plus lisse et hydratée après quelques utilisations. Le flacon est simple d’utilisation et pratique avec la pompe. Le produit est agréable à utiliser et à appliquer au quotidien et donne une sensation de confort dès l’application. Je recommande vivement . Produit offert par Influenster

Date published: 2026-05-14

Rated 5 out of 5 by ChristelleB from Très bon soin. [Cet avis a été recueilli en réponse à une offre.] Ce soin est vraiment génial, il a une texture ultraconfortable, pénètre rapidement, très agréable. Je sens ma peau réparée, hydratée et revitalisée... j'observe une diminution des signes de l'âge comme les ridules et les taches. Franchement, un très très bon soin.

Date published: 2026-05-13

Rated 5 out of 5 by GuillaumeC from Effet au top niveau [Cet avis a été recueilli en réponse à une offre.] Après quelques semaines d'utilisation de cette crème Skinceuticals, je souligne déjà être très surpris du produit qui outre le fait qu'il soit cher , il faut noter qu'on est sur un produit de haute qualité. La texture est légère ne laisse pas de gras, lisse bien la peau sans tiraillement et le teint est uniforme aussi. J'ai beaucoup apprécié cette crème qui chaque jour m'a apporté une sensation de peau plus rebondie. Sur le packaging rien a dire, cela présente super bien on dirait même une présentation de produit hightech et flacon pompe au top bon dosage.

Date published: 2026-05-12

Rated 5 out of 5 by CathyL from Bonne amélioration des signes visibles de l'âge ! [Cet avis a été recueilli en réponse à une offre.] Packaging très pratique de part son flacon pompe, permet un bon dosage. La texture est fluide, pénètre facilement et ne laisse pas de film gras. Cette crème hydrate bien la peau et au bout de 30 minutes environ on peut noter que la peau est plus rebondie, éclatante. Je l'utilise matin et soir après mon sérum et j'applique ensuite une protection solaire. Après quelques semaines d'utilisation je trouve que mes rides se sont légèrement atténuées, mes tâches se voient moins, peau plus lumineuse. A noter que je n'ai eu aucun effet indésirable. A continuer sur la durée pour des résultats encore plus visibles....

Date published: 2026-05-11

Rated 5 out of 5 by CandyM from La meilleure [Cet avis a été recueilli en réponse à une offre.] Cette crème est diablement efficace !! Elle est hyper agréable à utiliser et facile à appliquer la quantité est top aussi .aprea mes séances de laser ma peau est apaisée lissée réparée et elle continue le job pour uniformisé mon teint En plus elle dure longtemps.je ne peux plus m’en passer!

Date published: 2026-05-09

Rated 5 out of 5 by MalvinaP from Très bon produit [Cet avis a été recueilli en réponse à une offre.] J'ai tester ce produit c'est assez concluant : la texture est légère mais confortable elle pénètre vite dans la peau . Après quelques jours , la peau paraît plus lisse . Point fort : hydrate bien la peau , flacon pratique et hygiénique Le seul point négatif est peut être le prix qui est assez coûteux , et aussi le parfum qui peut ne pas plaire à tous le monde .

Date published: 2026-05-08

Rated 5 out of 5 by StephanL from Pour une peau plus belle [Cet avis a été recueilli en réponse à une offre.] La crème de jour anti âge de skinceustical est incroyable. La texture est fluide, elle pénètre rapidement sans être grasse, de suite elle apporte un confort a la peau. Son effet anti age et anti taches améliore clairement le teint. La crème est sans parfum et personnellement j'aime autant. Ma peau est plus saine et plus lumineuse

Date published: 2026-05-08

Advanced RGN-6 Reviews - page 2

Advanced RGN-6

Advanced RGN-6 Benefits

Skin rejuvenation cream

Advanced RGN-6 SCIENCE + PROOF

Visible Results

35%

36%

18%

Visible Results

35%

36%

18%

The Science Behind Advanced RGN-6

Key Ingredients

10% Glyco-Repair™

1% Eperuline

2% Niacinamide

3% Acetyl Tetrapeptide-9

0.2% Ectoin

0.2% Bioceramide 603

How to Use Advanced RGN-6

1

2

Complete Your Advanced RGN-6 Routine

C E Ferulic For Visible Signs of Ageing

Hyaluronic Acid Intensifier Multi-Glycan

Advanced RGN-6

Ultra Facial Defense SPF 50+ Facial Sunscreen for Ageing and Discolouration-Prone Skin 30ml

Pair Your In-Office Treatments with At-Home Products

In-Office

+

At-Home

Purchase option

Advanced RGN-6
SCIENCE + PROOF

The Science Behind
Advanced RGN-6

Pair Your In-Office Treatments with
At-Home Products