Discoloration Defense Serum

Discoloration Defense Serum is rated 4.3 out of 5 by 72.
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30 ml

High-potency serum targets visible skin discolouration for brighter, more even-looking skin

SKIN TYPES: Normal, Oily, Combination, Dry

SKIN CONDITION: Discolouration

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Discoloration Defense Serum is layerable, daily-use dark spot corrector serum clinically proven the reduce the appearance of key types of skin discolouration, including stubborn brown patches and post-blemish scars. Our latest generation formula improves the appearance of skin discolouration to reveal visibly brighter- looking skin.

Key Ingredients

  • 1.8% Tranexamic Acid
  • 5% Niacinamide
  • 5% Hepes
  • Features a synergistic blend of anti-discolouration and exfoliating ingredients to improve the appearance of skin discoloration including hyperpigmentation, post-blemish scars and stubborn brown spots.
  • Ideal at-home complement to professional skin discolouration treatments, such as chemical peels or non-ablative laser; always consult with a physician for individual regimen recommendations




In a 12-week clinical study, Discoloration Defense Serum significantly improved the appearance of key skin discolouration markers.

Average results were:

41% improvement in the appearance of stubborn brown patches*
46% improvement in the appearance of skin discolouration*
71% improvement in the appearance of post-blemish marks*
35% improvement in the appearance of an even skin tone*

*Improvement of score from visual gradings at 12 weeks, 63 subjects.

How To

How to use

  • Twice daily, apply 3-5 drops of Discoloration Defense serum to the face and neck
  • If using in the morning, apply after a SkinCeuticals vitamin C serum and follow with a SkinCeuticals broad spectrum SPF 30+ sunscreen
  • Limit sun exposure while using this product


Customer Reviews

Rated 3 out of 5 by from Interesting product I have been using this serum now for 4 weeks. The serum is slightly sticky on the skin but after absorbtion and use of moisturiser is not so bad. I have a few discoloured spots on my cheeks an a couple on my forehead and do feel that they have paled very slightly but not significantly enough to notice unless under close scrutiny. However I am hoping that with continued use I will see a diffirence. I am a great believer that the older your skin is the longer a product takes to work.My hope is that it will stop further discolouration. Will review again in a further 4 weeks if results change.
Date published: 2019-08-26
Rated 5 out of 5 by from Great Serum I have been using this serum now for 3 weeks. It’s not an overnight cure, no product can do that, but I have noticed a reduction in the intensity of my discolouration. I have areas on my cheek and forehead which are always worse in summer anyway. I think with continued use this will definitely help even out the skin tone and stop new areas of discolouration forming. It’s a lovely serum to use, it’s hydrating and gives a nice subtle glow to the skin. I use good skin care anyway but noticed a clearer complexion since using this product. Definitely will be adding this to my skin care arsenal.
Date published: 2019-08-29
Rated 5 out of 5 by from Amazing results I have had acne since my teenage years and to this day, I am 33 years old. Suffering from this skin condition has left me with lots of skin discolouration and scaring, especially on my chin and cheeks. I was given this product to try to treat my problem, it has done wonders so far, and I’ve only used it for a couple of weeks in the evening before my regular night cream. On top of adult acne, I have very sensitive skin and mild rosacea, however when using this product, it did not sting, and no flare ups. This truly works and it gave me so much more confidence, now that I don’t have to cover up the scaring caused from constant acne for the last 15 years so much. Thank you Skinceuticals for yet again another amazing product, you ROCK!!!
Date published: 2019-08-19
Rated 4 out of 5 by from Clarity I received this product 2 weeks ago I have suffered with malsama for 8 years now and I have tried every product available for this condition some help but as soon as I go in the sun it creeps back so I have to wear factor 50 even on rainy days. I found this product even after 1 weeks made my skin look clearer and brighter so if its this good after that short time I've high Hope's for a few months the consistency is also great skin feels hydrated
Date published: 2019-08-19
Rated 5 out of 5 by from It really works! I noticed a difference in the first few days of using this serum which I was sent to review. There was a definite brightness to the skin and clarity. It has helped to even my skin tone giving it radiance. I noticed that a few age spots have started to lighten already. I think using this product over a period of time will produce even better results. The serum itself caused no irritation to my skin and was easy to apply. It is definitely a serum I will now carry on using as the results were noticeable quickly. Fully worth 5 star rating.
Date published: 2019-08-24
Rated 3 out of 5 by from Not sure..... Only had a week to test this and I wish I could have had a little longer. I can't see any change in discolouration, it all still looks the same.... Also, can't make my mind up about the serum. It's a very light liquid and you only need a couple of drops, but when put on to the skin, it felt quite sticky and when I put on a moisturiser, it sometimes felt too sticky, not really happy about this. Also, during the day, my face would feel quite dry and I would have to add more moisturiser. Apart from the above, face did look a little brighter.....
Date published: 2019-08-19
Rated 4 out of 5 by from Great texture The texture of this is really refined; it’s not gritty in any way as cheaper niacinamide products I’ve tried have been and it has caused no irritation. I found that the colour of a cystic spot I had at the time of testing disappeared quickly so it appears to work well at reducing pigmentation, although I can’t speak to anything like melasma. I will continue to use it as I hope that the niacinamide content will help to redness and pore size too over time.
Date published: 2019-08-24
Rated 4 out of 5 by from Great so far... I was sent this to review and given that I had just returned from a few days in the sun was very interested in how it would deal with the regular hiperpignentation and acne marks. I’m a regular active user in my skincare routine but have never tried tranexamic acid. I love that it’s blended with nicinamide as it’s a favourite of mine for targeted pigmentation and also supporting skin structure. I had no reaction to the serum whatsoever and used 5 drops twice a day for two weeks so far. I’m really impressed so far and love that you wake up with a glow to your skin, from the brightening complex of actives ingredients. This product wasn’t harsh and didn’t cause me to break out. As you can see in my before (green shirt) and after (yellow) photos, my tan has been gently exfoliated, my pigmentation from my acne marks on my cheeks have faded slightly and I’m sure there’s a slight decrease in my pigmentation on my cheekbone and forehead. So far I’m impressed and am looking forward to continuing using the serum to see if/any further benefits I receive from it! The texture is fine, watery gel and easy to layer.
Date published: 2019-08-22
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