Main content
A smooth gradient of warm, peach-toned colors.

The different strengths of Retinol

If there is one ingredient to include in your anti-ageing skincare routine, it should be retinol. A derivative of vitamin A, retinol is clinically proven to even out your skin texture and reduce the signs of ageing. Retinol promotes skin renewal, which brightens skin tone and helps lessen the appearance of wrinkles.



Retinol strengths and retinol percentage 

Retinol skincare products come in a variety of strengths, with a higher retinol percentage making it look like it’s got more retinol in it, but it's the pure retinol content that matters. The SkinCeuticals retinol night cream features 0.3% pure retinol, and targets fine lines, wrinkles and discoloration through its controlled delivery system to ensure a steady, even release. The 0.3% pure retinol in the SkinCeuticals formulation is in-line with EU regulations which, since June 2024, has limited the retinol concentration in face products to 0.3% and in body products to 0.05%1. The change intends to reduce the risks of overuse to help prevent skin irritation.


A close-up of SkinCeuticals Retinol 0.3 night cream, showing a textured cream swatch and the product tube.

How to use retinol on the face 

Retinol should be applied sparingly and only in the evening. This helps limit the skin feeling sensitive after application and photosensitivity (skin being sensitive to the sun). Only use retinol once or twice a week to begin with, as this allows your skin time to get used to it. Dot a pea-sized amount of your preferred retinol product onto your finger and gently massage it into clean, dry skin. Take care not to apply too much product while also avoiding the delicate eye area as both can cause irritation. Do not apply retinol alongside Vitamin-C products which are typically applied in the morning. Do ensure you apply a broad spectrum sunscreen daily whilst using retinol.

UK Pharmacist Virginia Chachati says, “A little goes a long way when it comes to retinol, so use just enough to cover the surface of the skin to avoid irritation or redness. I recommend you use a daily sunscreen with SPF50 every morning to protect your skin, even on cloudy days. And make sure you reapply your sunscreen frequently and generously – this includes on top of makeup. Use a lower retinol dose or take a few days off if your skin starts to feel sensitive. Try applying a moisturiser rich in ceramides after you use retinol to prevent sensitivity.”

Want to try retinol on your neck? Tripeptide R-Neck Repair contains a neck specific dose of retinol (0.2%). This is a slightly reduced retinol dose to allow for the more delicate skin on the neck.   Once your skin is used to retinol being applied, you can think about applying your current percentage of retinol, such as 0.3%, more often. It can take a few weeks to build up to using it every other day, then daily.




Why retinol should always be used alongside sunscreen 

If you applied retinol last night, in the morning you should always apply a high-SPF, broad-spectrum sunscreen, as retinol will make your skin more sensitive to UV radiation from the sun which can damage the skin, these includes UVB and UVA rays. SkinCeuticals has a range of lightweight and effective sunscreens that protect the skin from UV radiation and free-radical damage while leaving it feeling soft and hydrated all day. Apply a broad-spectrum sunscreen such as Advanced Brightening UV Defense SPF 50 every morning.

1https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=OJ:L_202400996


A person applying SkinCeuticals Retinol 0.3 Refining Night Cream with 0.3% pure retinol from a white tube.

Please note, do not use Tripeptide-R-Neck repair in association with other products containing retinol or retinoids. 

Featured Products

Physician Insight Banner

Want to learn more about retinol and discover personalised skincare recommendations from a SkinCeuticals Skin Expert?


About Virginia Chachati MPharm

Virginia Chachati is a registered pharmacist with the UK General Pharmaceutical Council (GPhC) since 2014 and is PIF TICK certified. Chachati is a medical copywriter, creating evidence-based, accessible health information. Chachati has worked with the NHS, UKHSA, WHO, YouTube Health, and the Patient Information Forum (PIF).

Orientation message
For the best experience, please turn your device